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IT IS THE JOB OF RESPONSIBLE BREEDERS TO MAKE SURE THAT
THE BABIES THEY HELP PRODUCE ARE IN THE BEST OF HEALTH. ONE OF
THE WAY'S THEY CAN DO THIS IS TO DO THE TESTING THAT IS
RECOMMENDED ON THEIR ADULTS BEFORE BREEDING THEM.
I HAVE TO SAY IT IS VERY SCARY THAT A BREEDER OF YORKIE'S,
SHIH TZU'S AND SHORKIES WOULD NOT TEST THEIR DOGS FOR
GENETIC FAULTS!!!
THE FOLLOWING INFORMATION IS ON MILEEN'S WEBSITE
A Hybrid puppy is less likely to inherit any genetic
disease,
because there is no inbreeding.
Both Parents need to have the hereditary gene to pass on
any disease to the Hybrid puppy. This is very unlikely
because of the widened gene pool, with cross breeding only
F1, first Generation Dogs. The Hybrid dogs don't need to be
bred. The puppies health is in no danger, but the offspring
could be.
PLEASE NOTE:
The Shih Tzu and Yorkie Breed have several
health issues that run in BOTH their breeds. So any one of
these's health issues can be in a Shorkie weather it be a F1
F2 or a F3
Here is a list of a few issues:
Even if you
believe Mileen Coulters point of view. She states on her fancypoo4u.com
website breeds purebreds which are not mixes. So why are her purebreds not
already genetically tested???
MILEEN SAYS ON HER
SITE:
No OFA or cerf testing or screening to be
done on either of these breeds.
THIS IS A
LIE!!!
Eye Care for Animals
11950 West 110th Street
Suite A
Overland
Park, KS 66210
(913)-381-3937
BY HER POSTING THIS
AND THE OTHER INFORMATION ON HER GENETIC TESTING PAGE WE KNOW
SHE DOSE NOT DO ANY TYPE OF
TESTING ON HER MOM'S AND DADS. WHICH IS FINE, BUT DON'T
TELL PUPPY PARENTS THAT THE TESTING IS NOT THERE, EVERY ONE IS
ENTITLED TO THEIR OWN BELIEVES AND THEIR OWN BREEDING PROGRAM
BUT WHEN YOU ARE TELLING LIES TO SALE YOUR DOGS THAT IS WRONG..
DOSE YOUR BREEDER BELIEVE IN HYBRID VIGOR??
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Because of genetics, no dog regardless of
breed or cross is safe from inherited health issues. A big
myth that many less than ethical breeders of both purebreds
and designer mutts will use is that their dogs are
genetically free of all health issues. (Please for more on
this topic, read reknowned canine geneticist Dr. George
Padgett's article in Dog World from January of 1997
where he discusses the over 102 genetic issues that cross
bred dogs can have). Hybrid vigor does NOT exists in the
crossbred dog or the world of domestic dogs regardless of
what anyone states.
Well, first, many health issues have no
genetic test - just screenings. But even with this
knowledge, a good breeder will screen potential breeding
dogs. Since there are many health problems that can be
found in various and even all breeds, no breed or cross is
safe from them. It is up to the breeder to screen for what
they can and have the dogs certified where applicable (such
as OFA - Orthopedic Foundation of America).
Please click on the breeds in the
cross/designer mutt you are looking at. Compare the lists
and you will get an idea of what the cross can inherit.
Please note that the lists of
inheritable issues are not complete. Just the more common
hereditary or possible hereditary health issues are listed.
Also note, that some things most assume are not hereditary
may actually have a hereditary basis like predisposition to
ear infections and allergies or a predisposition to the
often fatal problem of "bloat." Hips dysplasia is found in
all breeds of dog from tiny to giants. It was discovered no
longer to be a "big dog" problem. Even if it is not listed
under the breed you are checking, please note that no breed
or cross is immune from this hereditary issue. Any breeder
should at least OFA or PennHip certify their dogs along with
CERF and Thyroid.
This list will frequently be added to.
Presently it is addressing the more common breeds seen in
the designer mutt/poo-dog phenomenon. The breed list is more
or less in alphabetical order - scroll down to find the
breeds you need to know about.
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Please note, these are
just brief descriptions of some of the
health issues
Epilepsy/Canine
Seizure Disorder
-
Hip Dysplasia
-
Progressive Retinal
Atrophy/Denegeration (PRA/PRD)
-
Temperaments
-
Allergies
-
Legg-Calves Perthe
-
Luxating Patellas
-
Hypothyroidism
-
Chryptochordism
-
Bloat
Mileen say's:
There are no Genetic tests or Screening for hereditary
diseases
This could NOT be more false:
Here is a list labs that do
DNA Testing
DNA testing based on identification of a specific gene
mutation is 100% accurate for identification of animals that
are clear
of the
disease (homozygous normal),
carriers
of the disease (phenotypically
normal but heterozygous for normal and mutant alleles), or
affected
with the
disease (homozygous for mutant alleles). Knowledge of the
genotypic status is the breeder’s most powerful tool for
elimination of a genetic disease. Breeding of genetically
clear
individuals
will produce offspring that are all genetically and
phenotypically normal. Breeding of a
clear
with a
carrier
will produce all
phenotypically normal offspring but 50% of the offspring are
expected to be genotypic
carriers.
In the rare incidence where desirable traits of an affected
individual outweigh the undesirable genetic trait, an
affected
individual may be
bred to a
clear and
the offspring will be all phenotypically normal but
genotypic
carriers.
These offspring
should later be bred only with
clear
individuals. DNA
testing by linkage is not as straight forward as that for
identification of a specific gene mutation and requires more
explanation than this space allows, but it is more desirable
than existing tests based on phenotypic evaluations of
polygenic traits. The financial advantages of DNA testing
and associated DNA profiling are clear. The test is
accurate, can be done at an early age, only one test is
required, and progeny can be cleared by parentage if DNA
profiles are available for determination of parentage. OFA
serves as the central repository of DNA test results from
approved laboratories for purposes of monitoring the disease
and as a source of information for breeders, breed clubs,
owners, prospective owners, and researchers.
Laboratories Performing DNA-Based Disease Tests
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Alfort School of Veterinary Medicine
CNM Project, Dr. Laurent Tiret
7 avenue du General de Gaulle
F-94704 Maisons-Alfort
CEDEX - FRANCE
Email: labo@labraodrcnm.com
Website: www.labradorcnm.com/pages/
site/0-frame_site.html
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Health Gene
2175 Keele St.
Toronto, ON M6M 3Z4 Canada
Toll Free: 1-877-371-1551
www.healthgene.com
Email: info@healthgene.com
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Mileen say:
with either the Shih tzu breed or the Yorkie
Breed.
www.vetgen.com
our response is yet they are on the OFA list for
DNA TESTING
VetGen
3728 Plaza Drive, Suite One
Ann Arbor, MI 48108
Phone: (800) 483-8436
www.vetgen.com
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Animal Health Trust
Genetics
Department
Lanwades Park, Kentford, Newmarket
Suffolk, CB8 7UU, U.K.
Telephone: 08700 50 24 24
Fax: 08700 50 24 25
E-mail:
dnatesting@aht.org.uk
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OptiGen, LLC
Cornell Business & Technology Park
767 Warren Road, Ste 300,
Ithaca, NY 14850
Phone: 607-257-0301, Fax: 607-257-0353
Email: genetest@optigen.com
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www.optigen.com
Dr. David Wenger
Dept of Neurology
Jefferson Medical College
1020 Locust St, 394
Philadelphia, PA 19107
Animal Molecular Genetics Lab
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Univ of MO College of Vet Medicine
320 Connaway Hall
Columbia, MO 65211
HansenL@missouri.edu
www.CanineGeneticDiseases.net
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Neurogenetics
Laboratory
Attn: Dr. Bai Jin Zeng
NYU Medical Center
400 East 34th Street (Room RR210)
New York, NY 10016
Phone: 212-263-2943
fyfe@cvm.msu.edu
Dr. Patrick Venta, Norfolk/Norwich Terr. |
Michigan State University
Laboratory of Comparative Medical
Genetics
2209 Biomedical Physical Sciences
East Lansing, MI 48824
Dr. John C. Fyfe, Curly Coated Retriever
517-355-6463
x1552 |
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Mary Boudreaux, DVM, PhD
Dept of Pathobiology
166 Greene Hall
College of Veterinary Medicine
Auburn University, AL 36849
(334) 844-2692
www.vetmed.auburn.edu/index.pl/
clinical_pathology
Email:
VCPL@vetmed.wsu.edu |
PennGen Laboratories
3850 Spruce Street
Philadelphia, PA 19104-6010
Phone: (215) 898-3375
http://w3.vet.upenn.edu/research/
centers/penngen/
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Washington State University–
Veterinary Clinical Pharmacology
Lab (WSU-VCPL)
PO Box 2280
Pullman, WA 99165-2280
Phone/FAX: 509-335-3745
www.vetmed.wsu.edu/depts-VCPL/test.asp |
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Cornell University Goldstein Molecular
and Genetics Laboratory
Richard E. Goldstein, DVM, DipACVIM,
DipECVIM-CA
Phone: 607-253-4480, Fax: 607-253-3534
E-mail: phpt@cornell.edu
www.vet.cornell.edu/faculty/Goldstein/ |
Veterinary Diagnostics Center
225 Corporate Court
Fairfield, OH 45014
Toll-Free: (800) 625-0874
www.vetdnacenter.com
Email:
contact@vetdnacenter.com |
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Hip Dysplasia
Abnormal development or growth in the hip
joint. Has both hereditary and environmental
factors. Polygenetic trait with no genetic
test as of now (however, there are
screenings to help determine if breeding
dogs are affected and to what severity). May
or may not be apparent in younger dogs.
Dogs can get a preliminary hip reading but
cannot be given a certification until at
least 24 months of age. Once thought to be a
large dog problem but has since been
diagnosed in just about every breed
regardless of size. All dogs regardless of
breed should be cleared through the OFA or
PennHip prior to breeding.
return to top
Progressive
retinal atrophy/degeneration
Hereditary blinding disorder that has
been identified in almost every breed of
dog. the retina basically degenerates and
leads to blindness over time. It is a simple
recessive trait. It may or may not be
apparent in puppies. Some dogs do not show
symptoms until they are adults. It can be
diagnosed with an opthalmascopic exam.
Since this is a progressive problem with no
genetic test as of now, just the screening,
breeding dogs must be checked annually and
the test results registered with the Canine
Eye Registration Foundation (CERF) through
Perdue University.
return to top
Epilepsy
Seizures can be brought on by many things
and can also be genetic. Until more is known
about how it is inherited, relatives of
affected dogs should have extreme caution
used when considering for breeding. There
are several types of seizures: RES (Reactive
Epileptic Seizure) is in response to a
stress; SES (Secondary) is a result of a
brain abnormality; PES (primary) seem to be
idiopathic (no known cause) and are
considered hereditary. Onset of seizures is
generally between one and five years of age.
There is no test for CES.
return to top
Poor
temperaments
Temperament is a combination of heredity
and what you do with it. Dogs with a
history of unsound temperaments may increase
the chance of producing puppies with unsound
temperaments. Final temperament also has
influences in the nurturing given to the
puppy as it grows. As with health issues,
breeding for sound temperament in vital.
return to top
allergies
Yes, allergies can have a hereditary
predisposition. Allergies can run in
families of dogs just as they can in
humans. A good breeder will have an idea if
there is a predisposition to allergies in
their lines. Some allergies can be pretty
benign while others could be fatal (like to
vaccines or anesthesia).
return to top
Legg-Calve-Perthes
Legg Calves Perthes Disease is a disease
where the femoral head begins to die. It is
unknown how the disease happens or mode of
inheritance. It is most often seen in
smaller breeds such as Toy and Miniature
Poodles,Westies, etc. However, it can also
occur in larger breeds. One or both legs
may be affected. This is most commonly seen
in younger dogs that are still growing.
return to top
luxating
patellas
Basically, the knee is not kept in proper
position and can slip out. This was commonly
thought to be a small dog issues but has
been seen in larger dogs as well. This can
be hereditary and depending on the severity,
may require surgery to correct.
return to top
hypothyroidism
Low thyroid levels and can be hereditary
in nature. Low thyroid can lead to various
other issues. There are multiple symptoms
associated with hypothyroid and this problem
can be detected with a blood test. Some dogs
may screen fine when younger but develop it
later in life.
return to top
cryptochordism
This is undescended testicles (can be
single - monorchid). This can have a
hereditary basis and if left untreated can
lead to health issues down the road for the
male. Dogs that have a single undescended
testicle may still be fertile but the
problem can be passed on. Again, if the
testicles are left in the body, they can
lead to complications. Dogs with this
condition should be neutered and breeding
lines evaluated.
return to top
gastric
torsion/bloat
This very serious issue can also have a
hereditary predisposition. Bloat is a
catchall term for a few conditions where for
one reason or another (blockage, twist,
etc.) gas cannot be expelled from the
abdomen and the stomach and intestinal
tissue can die causing serious complications
and death. This is not just a large or deep
chested breed problem as commonly thought.
And it has been thought that there are
hereditary predisposition in some dogs to
this.
return to top
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Because
of genetics, no dog regardless of breed or cross is safe from inherited
health issues. A big myth that many less than ethical breeders of both
purebreds and designer mutts will use is that their dogs are genetically
free of all health issues.
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